7 Severe Side Effects of Addyi : Addyi (Flibanserin), the first medication for HSDD – hypoactive sexual desire disorder in women, was approved by the FDA in 2015.
Prior to its approval, the drug was extensively backed by women’s groups and coalitions, who pointed out that while there were various pharmaceuticals for sexual activity available for males (e.g., sildenafil), there were none available for women.
10% to 40% of women experience libido problems as a result of hypoactive sexual desire disorder (HSDD), also known as female sexual interest/arousal condition (Jaspers, 2016).
A person with HSDD, has a lack of sexual desire that is stressful or aggravating but isn’t caused by a physical problem (such as a side effect of a medication that you take or an underlying medical or mental health condition). Continue reading to learn more about Addyi symptoms and some precautions to take.
Why Is Addyi Used?
Addyi, also named the “little pink pill,” is a prescription medication used to treat reduced sexual desire in premenopausal women. It was licensed by the Food and Drug Administration (FDA) in 2015 and is accessible in the form of a 100-milligram oral tablet, which is taken once a day at bedtime typically (FDA, 2021).
Addyi is known as “the female Viagra,” although she is not the same as Viagra. The FDA has approved Viagra to treat erectile dysfunction in men. Women with sexual dysfunction may be prescribed sildenafil off-label by healthcare practitioners (that includes problems with arousal and orgasm, as well as pain during sex). Nonetheless, research on the efficacy of sildenafil in women is conflicting.
Sexual desire, particularly in women, is a complicated physical and emotional experience. Addyi differs from Viagra in that it is supposed to function in the brain, where it aids in the emotional aspect of sexual desire.
7 Side Effects of Addyi
The clinical trial data on flibanserin provided to the FDA contained results from over 11,000 people, making it one of the largest data sets ever presented to the FDA. This medication’s safety has been scrutinized more rigorously than the safety of most new medications approved by the FDA.
Having said that, flibanserin, like any other recently licensed medicine, still has a lot of unknowns. Rare but major adverse effects are sometimes found months or years after a medicine has been widely used. Expect your prescriber to closely monitor your treatment.
Not everyone who uses Addyi experiences adverse effects. However, if you have liver problems, take certain drugs, or consume alcohol while taking Addyi, you may be more susceptible to side effects.
Immediately consult a doctor if you encounter any of the following effects after taking flibanserin:
- Dehydration And Unusual Thirst
- Drowsiness Or Sleepiness
- Sedation, And Spinning Sensation
- Fainting
- Cold, Clammy, And/Or Pale Skin
- Lack Of Concentration
- Weak And Rapid Heartbeat
If you are suffering extreme tiredness, seek medical attention. Fainting or dizziness due to a drop in blood pressure was less common. However, significant decreases in blood pressure were observed in many people in so-called “challenge tests,” in which volunteers received flibanserin along with drugs known to boost blood levels of the drug or took the drug and then drank the equivalent of 2-4 shots of liquor.
Addyi Precautions to Focus On
Certain drugs should be avoided
When Addyi is used with certain drugs, it might result in very low blood pressure, tiredness, and fainting (loss of consciousness).
Avoid using Addyi if you are taking any of the these mentioned drugs, according to the manufacturer:
- Medications used to treat HIV-1 infection
- Some antifungal medicines
- Particular antibiotics
- Some medications used to treat hepatitis C infections
- Some drugs for treating high blood pressure, chest pain (angina), and other heart disorders.
- Nefazadone (used to treat depression)
Consult your healthcare practitioner or pharmacist if you are unsure whether a medicine you are taking interacts with Addyi.
Using Addyi while drinking booze
If you drink alcohol while taking Addyi, you run the risk of getting low blood pressure and losing consciousness.
If you do decide to drink alcohol while taking Addyi, here are some tips to follow:
- Wait a minimum of two hours after consuming one or two ordinary alcoholic beverages before taking Addyi and going to bed. One 12-ounce ordinary beer, five ounces of wine, and 1.5 ounces of distilled spirits are examples of standard alcoholic beverages (approximately one shot).
- If you have 3 or more standard alcoholic drinks in the evening, skip your Addyi dose at bedtime.
Grapefruit
Taking Addyi with grapefruit may increase the drug’s quantity in your system and the severity of the negative effects. While using Addyi, avoid drinking grapefruit juice or consuming excessive amounts of grapefruit.
Important information concerning ADDYI that you must know – Summary
You are more likely to experience side effects or get extreme low blood pressure and fainting (loss of consciousness) if you take ADDYI and:
- Consume alcohol near the time you take your ADDYI dosage.
- Wait at least 2 hours after drinking 1 or 2 standard alcoholic drinks before taking Addyi at bedtime.
- If you have three or more standard alcoholic beverages in the evening, you should forgo your ADDYI dose at bedtime.
- Do not consume alcohol after taking your ADDYI at bedtime till the next day.
- Use some prescription or over-the-counter medications or herbal supplements. While using ADDYI, do not take or begin taking any prescription medications, over-the-counter medications, or herbal supplements unless you first consult with your doctor. Your doctor will advise you whether it is okay to take other medications or herbal supplements while taking ADDYI.
- Have liver issues. If you have liver problems, do not take ADDYI. If you take ADDYI and feel lightheaded or dizzy, immediately lie down. If the symptoms do not go away or you feel like you might faint, seek emergency medical attention or have someone seek emergency medical attention for you (lose consciousness). Inform your doctor immediately if you faint.
Addyi might not be suitable for everyone. Your healthcare practitioner will review your medical history, including any medical issues you have, before prescribing Addyi. You should notify them if you are pregnant or nursing or if you have (or have had) issues controlling your alcohol intake, liver problems, or an adverse reaction to Addyi or its constituents.
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7 Severe Side Effects of Addyi
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